Plant Transcription Factor Database
Previous version: v3.0
Tarenaya hassleriana
EIL Family
Species TF ID Description
XP_010519194.1EIL family protein
XP_010519752.1EIL family protein
XP_010521598.1EIL family protein
XP_010521599.1EIL family protein
XP_010521601.1EIL family protein
XP_010521602.1EIL family protein
XP_010521603.1EIL family protein
XP_010527327.1EIL family protein
XP_010537472.1EIL family protein
XP_010537473.1EIL family protein
XP_010544311.1EIL family protein
XP_010544312.1EIL family protein
XP_010544313.1EIL family protein
XP_010546410.1EIL family protein
XP_010554461.1EIL family protein
XP_010554462.1EIL family protein
XP_010554463.1EIL family protein
XP_010557480.1EIL family protein
XP_010557481.1EIL family protein
XP_010557482.1EIL family protein
XP_010557483.1EIL family protein
EIL Family Introduction

The gaseous phytohormone ethylene regulates various processes related to growth, development, and stress response of higher plants. A largely linear pathway of ethylene signaling was revealed by a number of molecular genetic studies. In the pathway, Ethylene-insensitive3 (EIN3) and EIN3-like (EIL) proteins are the key transcription factors. The EIN3/EIL proteins were shown to regulate expression of the GCC-box-binding transcription factors, ethylene-response factors. It is known that the phenotype of the Arabidopsis thaliana EIN3 (AtEIN3)-deficient mutants, e.g. long seedlings in the presence of ethylene or its precursor, is suppressed by overexpression of Arabidopsis EIL1 (AtEIL1) or EIL2 (AtEIL2), indicating the functional equivalence of these proteins.

In the present study, a region corresponding to the major DBD of the EIN3/EIL transcription factor family, which is the key factor in the ethylene signaling, was identified. The isolated domain exists in a monomeric form and retained the sequence specificity for the DNA binding. The structure determined by NMR spectroscopy consists of five alpha-helices, packing into a novel fold dissimilar to known DBDs. An NMR titration analysis suggested that a region including the key mutation site, ein3-3 site, was shown to be involved in DNA binding.

Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Tomo Y, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J Mol Biol, 2005. 348(2): p. 253-64.
PMID: 15811366